Abstract:

Using BaCl₂, TiCl₄ and NaOH as raw materials, BaTiO₃ particles with nanometer spherical morphology were prepared by the method of microchannel continuous precipitation. The effects of barium concentration, volume flow rate, reaction temperature and flow ratio of two branches on the morphology and particle size of the products were investigated. And the products were compared with those obtained by batch precipitation. The results show that spherical BaTiO₃ particles with uniform particle size distribution can be prepared under the condition of 90℃, 0.15 mol/L Ba concentration, 3 mol/L alkali concentration, and 2 ml/min of each branch volume flow. The particle size of prepared powders was 80－150 nm. The obtained BaTiO₃ diffusion layer was applied to the creatine kinase dry sheet, and the repeatability was good. Besides, the apparent concentration gradient was showed, and the relationship between the light reflectance value and the concentration was corresponding to the reaction phenomenon. The results have high reliability, indicating that the BaTiO₃ particles obtained by the microchannel continuous precipitation method are feasible to be applied in medical test dry film.

Key words: microchannel, precipitation, preparation, BaTiO₃, medical test dry film

摘要：

以BaCl₂、TiCl₄、NaOH为原料，采用微通道连续沉淀法制备纳米级球形形貌的BaTiO₃颗粒。考察了钡浓度、体积流量、反应温度及两分支物料流量比等因素对产物形貌及粒径大小的影响，并将其与间歇沉淀法得到的产物进行了比较。实验结果表明：钡浓度0.15 mol/L，碱浓度3 mol/L，两分支物料体积流量均为2 ml/min，反应温度90℃条件下可制备得到具有规整球形形貌、粒径分布均匀的纳米级BaTiO₃颗粒，其粒径为80～150 nm。最后，将所得BaTiO₃扩散层应用到肌酸激酶干片中，重复性较好，且浓度梯度明显，光反射率值与浓度的关系与之对应。结果具有较高的可信度，说明微通道连续沉淀法得到的BaTiO₃颗粒在医用干片上应用是可行的。

关键词: 微通道, 沉淀, 制备, BaTiO₃, 医学检测干片