关键词: (顺)-1, 1, 1, 4, 4, 4-六氟-2-丁烯, 发泡剂, 合成方法

Abstract: Hydrofluoroolefin cis-1,1,1,4,4,4-hexafluoro-2-butene (Z-HFO-1336) has zero ozone depletion potential (ODP) and low global warming potential (GWP)，which replaces trichlorofluoromethane CFC-11，1,1-dichloro-1-fluoroethane HCFC-141b，and 1,1,1,3,3- pentafluoropropane HFC-245fa by good compatibility and chemical stability，is used as new generation foaming materials. Synthesis of the compound mainly includes three types：direct fluorination of C4 compounds，coupling of CFC-113 and HCFC-123，and telomerization of haloalkane with olefin to form chlorofluorobutane by Kharasch reaction. Direct method is too expensive for large scale production，coupling route brings up pollution problems，and complicated Kharasch reaction involves long steps. Two synthesis approaches are proposed：Coupling of HCFC-123 attracts theoretical study，which involves activation of C─Cl bond and single electron transfer process，and simple and practical way using ethylene or trifluoropropene as starting material could be an effective method for plant-scale production.

Key words: cis-1,1,1,4,4,4-hexafluoro-2-butene, blowing agent, synthetic