Research progress in effect of gel on crystallization process

doi:10.11949/0438-1157.20190754

Abstract

Abstract:

Compared with the traditional solution phase crystallization, when the gel is used as a crystallization medium, it can suppress convection and reduce the diffusion of the solute molecules. So a high supersaturation without causing explosive nucleation can be obtained and allowing the solute molecules continuous growth on the crystal surface. Gel is also possible to provide as a template or active nucleation sites by designing a specific gel agent. It makes the crystallization in gel is an effective control means and causes extensive attention. This paper reviews how polymer gel, supramolecular gels and inorganic gels can effectively control the nucleation and growth rate, regulate polymorphism, crystal habit and particle size. The role of microgels in solution phase crystallization and the future development trend of gel phase crystallization are briefly introduced.

Key words: gel, crystallization, polymorphism, crystal habit, particle size distribution

摘要：

相比于传统的溶液相结晶，凝胶用作结晶介质时，由于能抑制对流和减慢溶质分子的扩散，除了能提供较大的过饱和度且不会导致爆发成核，以及使溶质分子在生长面上连续地生长之外，还可以通过设计特定的凝胶剂为溶质分子提供模板或者活性成核位点，这使得凝胶相结晶成为了一种有效的结晶控制手段，引起了研究人员的广泛关注。综述了高分子凝胶、超分子凝胶以及无机凝胶如何有效地控制结晶成核和生长的速度，调控晶型、晶习和晶体粒度，简单介绍了微凝胶在溶液相结晶中的作用，以及凝胶相结晶未来的发展趋势。

关键词: 凝胶, 结晶, 晶型, 晶习, 粒度分布

CLC Number:

TQ 420.6⁺1

Wencheng ZHANG,Junbo GONG,Weibing DONG,Songgu WU. Research progress in effect of gel on crystallization process[J]. CIESC Journal, 2020, 71(2): 487-499.

张文铖,龚俊波,董伟兵,吴送姑. 凝胶对结晶过程影响的研究进展[J]. 化工学报, 2020, 71(2): 487-499.

Figures/Tables 2

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