CIESC Journal ›› 2021, Vol. 72 ›› Issue (1): 320-333.DOI: 10.11949/0438-1157.20201089
• Reviews and monographs • Previous Articles Next Articles
WANG Lian(),WU Di,ZHOU Jingwen()
Received:
2020-08-03
Revised:
2020-10-24
Online:
2021-01-05
Published:
2021-01-05
Contact:
ZHOU Jingwen
通讯作者:
周景文
作者简介:
王炼(1992—),男,博士研究生,基金资助:
CLC Number:
WANG Lian, WU Di, ZHOU Jingwen. Research progress of lignans biosynthesis and their microbial production[J]. CIESC Journal, 2021, 72(1): 320-333.
王炼, 吴迪, 周景文. 木脂素的生物合成及其微生物法生产的研究进展[J]. 化工学报, 2021, 72(1): 320-333.
木脂素类别 | 典型化合物 | 天然来源 | 生物活性 | 其他合成方式 |
---|---|---|---|---|
芳基萘 | 山荷叶素 | 丘生闭花木 | 治疗胃癌 | 无报道 |
赛菊芋黄素 | 台湾杉 | 抑制脑肿瘤转移 | 无报道 | |
芳基四氢萘 | 鬼臼毒素 | 桃儿七、足叶草 | 抗肿瘤药物的前体 | 内生菌TW5 |
南烛木树脂酚 | 小果南烛 | 皮肤美白剂 | 植物细胞培养 | |
双并四氢呋喃 | 松脂素 | 木本植物、纤维植物 | 抗细菌和真菌、改善记忆障碍 | 植物细胞培养、微生物发酵 |
芝麻素 | 芝麻 | 抑制和阿尔兹海默症相关的部分症状 | 微生物发酵 | |
二苄基丁内酯 | 罗汉松脂素 | 种子、蔬菜和水果 | 抗氧化、抗雌激素、抗骨质疏松 | 微生物发酵、化学合成 |
牛蒡酚 | 牛蒡 | 降低收缩血压 | 无报道 | |
二苯并环辛二烯 | 五加前胡素 | 剑叶菊 | 未用于药物治疗 | 化学合成 |
二芳基丁烷 | 叶下珠脂素 | 叶下珠 | 抑制HepG2的增殖 | 无报道 |
二苄基丁酸乳酯 | 荜澄茄素 | 木材、根和树脂 | 镇痛、消炎 | 无报道 |
呋喃 | 落叶松脂素 | 菲律宾茜草 | 抗菌、抗氧化 | 微生物发酵 |
Table 1 The categories of lignans and the basic characters of typical compounds
木脂素类别 | 典型化合物 | 天然来源 | 生物活性 | 其他合成方式 |
---|---|---|---|---|
芳基萘 | 山荷叶素 | 丘生闭花木 | 治疗胃癌 | 无报道 |
赛菊芋黄素 | 台湾杉 | 抑制脑肿瘤转移 | 无报道 | |
芳基四氢萘 | 鬼臼毒素 | 桃儿七、足叶草 | 抗肿瘤药物的前体 | 内生菌TW5 |
南烛木树脂酚 | 小果南烛 | 皮肤美白剂 | 植物细胞培养 | |
双并四氢呋喃 | 松脂素 | 木本植物、纤维植物 | 抗细菌和真菌、改善记忆障碍 | 植物细胞培养、微生物发酵 |
芝麻素 | 芝麻 | 抑制和阿尔兹海默症相关的部分症状 | 微生物发酵 | |
二苄基丁内酯 | 罗汉松脂素 | 种子、蔬菜和水果 | 抗氧化、抗雌激素、抗骨质疏松 | 微生物发酵、化学合成 |
牛蒡酚 | 牛蒡 | 降低收缩血压 | 无报道 | |
二苯并环辛二烯 | 五加前胡素 | 剑叶菊 | 未用于药物治疗 | 化学合成 |
二芳基丁烷 | 叶下珠脂素 | 叶下珠 | 抑制HepG2的增殖 | 无报道 |
二苄基丁酸乳酯 | 荜澄茄素 | 木材、根和树脂 | 镇痛、消炎 | 无报道 |
呋喃 | 落叶松脂素 | 菲律宾茜草 | 抗菌、抗氧化 | 微生物发酵 |
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