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Kinetics of the Double Carbonylation of Benzylchloride

OUYANG Pingkai; FAN Weiping; ZHANG Shi   

  1. College of Pharmaceutics and Life Science, Nanjing University of Chemical Technology,
    Nanjing 210009, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2000-12-18 Published:2000-12-18
  • Contact: OUYANG Pingkai

氯苄双羰基化反应动力学

欧阳平凯; 范伟平; 张湜   

  1. College of Pharmaceutics and Life Science, Nanjing University of Chemical Technology,
    Nanjing 210009, China
  • 通讯作者: 欧阳平凯

Abstract: It is a multi-phase-catalyzed reaction to produce calcium phenylpyruvate by double
carbonylation of benzylchloride. Based on the analysis of the reaction mechanism, a kinetic
model of the carbonylation reaction was obtained. The model was verified through
experiments in which the diffusion effect was neglected with the appropriate operation
manner. But it is inevitable that the carbonylation process is controlled by diffusion as
the autoclave scaling up.

Key words: benzylchloride, carbonylation, kinetics

摘要: It is a multi-phase-catalyzed reaction to produce calcium phenylpyruvate by double
carbonylation of benzylchloride. Based on the analysis of the reaction mechanism, a kinetic
model of the carbonylation reaction was obtained. The model was verified through
experiments in which the diffusion effect was neglected with the appropriate operation
manner. But it is inevitable that the carbonylation process is controlled by diffusion as
the autoclave scaling up.

关键词: benzylchloride;carbonylation;kinetics