Preparation of Conjugated Linoleic Acid and Identification of Its Isomers

Abstract

Abstract: Conjugated linoleic acid (CLA) is a kind of fatty acid with physiological activities and
potential application prospect. A synthesis method of conjugated linoleic acid and a
purification technology were studied. CLA was prepared and purified by urea-complexation
and conjugation using safflower oil as raw material. The purity of CLA and total recovery
of the product was more than 95% and 48%, respectively. The main isomers produced in
alkali-catalyzed conjugation were identified by gas chromatography (GC) linked to mass
spectrometry (MS) and Fourier transform infrared spectroscopy (FTIR). The total amount of
the two main isomers (9cis, 11trans-and 10trans, 12cis-CLA) determined by GC was more than
90% of the product.

Key words: linoleic acid, conjugated linoleic acid, urea-complexation, alkali-catalyzed conjugation, identification, safflower oil

摘要： Conjugated linoleic acid (CLA) is a kind of fatty acid with physiological activities and
potential application prospect. A synthesis method of conjugated linoleic acid and a
purification technology were studied. CLA was prepared and purified by urea-complexation
and conjugation using safflower oil as raw material. The purity of CLA and total recovery
of the product was more than 95% and 48%, respectively. The main isomers produced in
alkali-catalyzed conjugation were identified by gas chromatography (GC) linked to mass
spectrometry (MS) and Fourier transform infrared spectroscopy (FTIR). The total amount of
the two main isomers (9cis, 11trans-and 10trans, 12cis-CLA) determined by GC was more than
90% of the product.

关键词: linoleic acid;conjugated linoleic acid;urea-complexation;alkali-catalyzed conjugation;identification;safflower oil

GUO Zheng, ZHANG Genwang, SUN Yan. Preparation of Conjugated Linoleic Acid and Identification of Its Isomers[J]. .

郭诤, 张根旺, 孙彦. 高纯度共轭亚油酸的规模化制备及其异构体的鉴定[J]. CIESC Journal.

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