CIESC Journal ›› 2024, Vol. 75 ›› Issue (11): 3935-3950.DOI: 10.11949/0438-1157.20240502

• Reviews and monographs • Previous Articles     Next Articles

Research progress on droplet sieving in microchannel

Hao CHEN(), Wenqi ZHAO, Haoyu FENG, Taotao FU, Chunying ZHU, Youguang MA()   

  1. State Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
  • Received:2024-05-08 Revised:2024-06-08 Online:2024-12-26 Published:2024-11-25
  • Contact: Youguang MA

微通道内液滴筛分的研究进展

陈昊(), 赵文琪, 冯浩宇, 付涛涛, 朱春英, 马友光()   

  1. 天津大学化工学院,化学工程联合国家重点实验室,天津 300072
  • 通讯作者: 马友光
  • 作者简介:陈昊(1999—),男,硕士研究生,hchen_2022@tju.edu.cn

Abstract:

Droplet sieving is one of the basic operations of droplet microfluidic technology. Compared to the droplet sieving technology in traditional macroscopic equipment, the continuous operation of droplet sieving could be easily conducted in microfluidic equipment, and the whole process of droplet generation, sieving and collection could be continuously realized by using a microfluidic chip. This technology has been widely used in cell encapsulation, drug screening, gene analysis and other important fields. The droplet sieving based on microfluidic technology could be divided into active sieving and passive sieving. In this paper, the research progress of droplet sieving in microchannel in recent years is reviewed, and the future research directions and problems to be solved in this field are prospected.

Key words: microchannel, microdroplet, droplet sieving, multiphase flow

摘要:

液滴筛分是液滴微流控技术的基本操作之一。与传统宏观设备中的液滴筛分技术相比,微流控液滴筛分技术可实现连续化操作,能够在一个微流控芯片上实现从液滴生成到筛分再到收集的全过程连续化生产,该技术已广泛应用于细胞封装、药物筛选、基因分析等领域。基于微通道的液滴筛分技术可分为主动筛分和被动筛分,综述了近年来微通道内液滴筛分技术的研究进展,并对该领域未来的研究方向和需要解决的问题进行了展望。

关键词: 微通道, 微液滴, 筛分, 多相流

CLC Number: