CIESC Journal ›› 2020, Vol. 71 ›› Issue (10): 4520-4531.DOI: 10.11949/0438-1157.20200214
• Reviews and monographs • Previous Articles Next Articles
Yanqin XU1(),Xizhi YANG1,Ruoshi LUO1,Yuhong HUANG2,Feng HUO2,Dan WANG1()
Received:
2020-03-02
Revised:
2020-04-25
Online:
2020-10-05
Published:
2020-10-05
Contact:
Dan WANG
徐彦芹1(),杨锡智1,罗若诗1,黄玉红2,霍锋2,王丹1()
通讯作者:
王丹
作者简介:
徐彦芹(1984—),女,博士研究生,高级工程师,基金资助:
CLC Number:
Yanqin XU, Xizhi YANG, Ruoshi LUO, Yuhong HUANG, Feng HUO, Dan WANG. Application of synthetic biology in manufacture of bio-based plastics[J]. CIESC Journal, 2020, 71(10): 4520-4531.
徐彦芹, 杨锡智, 罗若诗, 黄玉红, 霍锋, 王丹. 合成生物学在生物基塑料制造中的应用[J]. 化工学报, 2020, 71(10): 4520-4531.
工程细菌或工程细胞 | 改造方式/手段 | 原料 | 产物单体/生物基材料 | 应用 | 文献 |
---|---|---|---|---|---|
Escherichia coli | 丙酰辅酶A转移酶(pct)以及真养产碱杆菌的PHA合成酶等基因 | 葡萄糖 | 3HV | PHA | [ |
Escherichia coli | 大肠杆菌中导入固氮菌属的phaABC基因和phaP基因 | 甘油 | PHB | PHB | [ |
烟草 | 烟草中导入含有不动杆菌属和巨大芽孢杆菌基因 | CO2 | PHB | PHB | [ |
Escherichia coli | 敲除基因消除代谢途径;过表达赖氨酸脱羧酶基因 | 葡萄糖 | 戊二胺 | 尼龙5,4和尼龙5,6等 | [ |
Corynebacterium glutamicum | 大肠杆菌中的木糖异构酶基因xylA、木酮糖激酶基因xylB与赖氨酸脱羧酶基因cadA在谷氨酸棒状杆菌中共表达 | 木糖 | 戊二胺 | 尼龙5,10和尼龙5,12等 | [ |
Corynebacterium glutamicum | 培养基中添加吐温40 | 葡萄糖 | 戊二胺 | 尼龙5,4和尼龙5,12等 | [ |
Escherichia coli | 基因DavB和DavA过表达 | 酪氨酸 | 5-氨基戊酸 | 尼龙5和尼龙6,5等 | [ |
Escherichia coli | 基因LeuA、LeuB、LeuC、LeuD、KivD和PadA过表达 | 酪氨酸 | 6-氨基己酸 | 尼龙6 | [ |
Escherichia coli | 乙酸激酶基因ackA敲除,过表达乳酸脱氢酶基因LDH | 葡萄糖 | PLA | PLA | [ |
Escherichia coli | 导入丙酮酸羧化酶基因pyc | 葡萄糖 | 丁二酸 | PBS | [ |
Table 1 Examples of applications of engineered bacteria or engineered cells to produce bio-based plastics
工程细菌或工程细胞 | 改造方式/手段 | 原料 | 产物单体/生物基材料 | 应用 | 文献 |
---|---|---|---|---|---|
Escherichia coli | 丙酰辅酶A转移酶(pct)以及真养产碱杆菌的PHA合成酶等基因 | 葡萄糖 | 3HV | PHA | [ |
Escherichia coli | 大肠杆菌中导入固氮菌属的phaABC基因和phaP基因 | 甘油 | PHB | PHB | [ |
烟草 | 烟草中导入含有不动杆菌属和巨大芽孢杆菌基因 | CO2 | PHB | PHB | [ |
Escherichia coli | 敲除基因消除代谢途径;过表达赖氨酸脱羧酶基因 | 葡萄糖 | 戊二胺 | 尼龙5,4和尼龙5,6等 | [ |
Corynebacterium glutamicum | 大肠杆菌中的木糖异构酶基因xylA、木酮糖激酶基因xylB与赖氨酸脱羧酶基因cadA在谷氨酸棒状杆菌中共表达 | 木糖 | 戊二胺 | 尼龙5,10和尼龙5,12等 | [ |
Corynebacterium glutamicum | 培养基中添加吐温40 | 葡萄糖 | 戊二胺 | 尼龙5,4和尼龙5,12等 | [ |
Escherichia coli | 基因DavB和DavA过表达 | 酪氨酸 | 5-氨基戊酸 | 尼龙5和尼龙6,5等 | [ |
Escherichia coli | 基因LeuA、LeuB、LeuC、LeuD、KivD和PadA过表达 | 酪氨酸 | 6-氨基己酸 | 尼龙6 | [ |
Escherichia coli | 乙酸激酶基因ackA敲除,过表达乳酸脱氢酶基因LDH | 葡萄糖 | PLA | PLA | [ |
Escherichia coli | 导入丙酮酸羧化酶基因pyc | 葡萄糖 | 丁二酸 | PBS | [ |
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