• •
宋璟1(), 王玉军1, 邓建1, 陈光文2, 骆广生1()
收稿日期:
2024-05-26
修回日期:
2024-06-20
出版日期:
2024-06-25
通讯作者:
骆广生
作者简介:
宋璟(1997—),男,博士研究生,songj23@mails.tsinghua.edu.cn
基金资助:
Jing SONG1(), Yujun WANG1, Jian DENG1, Guangwen CHEN2, Guangsheng LUO1()
Received:
2024-05-26
Revised:
2024-06-20
Online:
2024-06-25
Contact:
Guangsheng LUO
摘要:
芳烃的硝化反应作为工业生产中最重要的基本反应类型之一,随着化学品安全、绿色、高效生产的要求,其反应工艺向微尺度方向的发展已是必然的趋势。如何实现微尺度芳烃硝化反应的高质量发展,是重大工程前沿方向之一。全面综述并剖析了硝化微反应工艺的发展和面临的问题,从微尺度硝化反应动力学研究入手,为芳烃硝化微反应工艺设计及强化指明方向,并总结了当前硝化微反应工艺中的过程强化及安全性评价方法,最后对其未来发展方向进行了展望。
中图分类号:
宋璟, 王玉军, 邓建, 陈光文, 骆广生. 微反应器内芳烃硝化反应研究进展[J]. 化工学报, DOI: 10.11949/0438-1157.20240558.
Jing SONG, Yujun WANG, Jian DENG, Guangwen CHEN, Guangsheng LUO. Research progress of aromatic nitration reaction in microreactors[J]. CIESC Journal, DOI: 10.11949/0438-1157.20240558.
图2 芳烃硝化微尺度反应动力学研究实验装置示意图[32, 34, 35, 40, 46]
Fig.2 Schematic diagram of experimental apparatus for the kinetic study of aromatics nitration at microscale[32, 34, 35, 40, 46]
作者(年份) | 硝化底物 | 相态 | Ea/kJ·mol-1 | lnA | |
---|---|---|---|---|---|
Zhang(2016)[ | 乙酰愈创木酚 | 均相 | 139 | — | |
Li(2017)[ | 2-乙基己醇 | 均相 | 42.67 | — | |
Wen(2018)[ | 三氟甲氧基苯 | 非均相 | 29.3(邻位) | 8.75(邻位) | |
26.9(对位) | 9.64(对位) | ||||
Song(2021)[ | 对硝基甲苯 | 均相 | 50.21 | 58.39 | |
邻硝基甲苯 | 72.36 | 66.73 | |||
Lan(2021)[ | 邻二氯苯 | 非均相 | 30.96 | — | |
Cui(2021)[ | 氯苯 | 均相 | 25.98 | — | |
Song(2023)[ | 甲苯 | 非均相 | 28.00 | 100.15 | |
Jin(2023)[ | 硝基苯 | 非均相 | 71.23 | 7.81 | |
Guo(2023)[ | 三氟甲基苯 | 非均相 | 86.33 | — |
表1 微尺度芳烃硝化反应动力学文献总结
Table 1 Summary of literatures on the kinetic study of microscale aromatic nitration
作者(年份) | 硝化底物 | 相态 | Ea/kJ·mol-1 | lnA | |
---|---|---|---|---|---|
Zhang(2016)[ | 乙酰愈创木酚 | 均相 | 139 | — | |
Li(2017)[ | 2-乙基己醇 | 均相 | 42.67 | — | |
Wen(2018)[ | 三氟甲氧基苯 | 非均相 | 29.3(邻位) | 8.75(邻位) | |
26.9(对位) | 9.64(对位) | ||||
Song(2021)[ | 对硝基甲苯 | 均相 | 50.21 | 58.39 | |
邻硝基甲苯 | 72.36 | 66.73 | |||
Lan(2021)[ | 邻二氯苯 | 非均相 | 30.96 | — | |
Cui(2021)[ | 氯苯 | 均相 | 25.98 | — | |
Song(2023)[ | 甲苯 | 非均相 | 28.00 | 100.15 | |
Jin(2023)[ | 硝基苯 | 非均相 | 71.23 | 7.81 | |
Guo(2023)[ | 三氟甲基苯 | 非均相 | 86.33 | — |
图4 几种具有优异分散和传质性能的新型微反应器结构[44, 54, 56, 57, 63, 65]
Fig.4 Several novel microreactors with excellent microdispersion and mass transfer performance[44, 54, 56, 57, 63, 65]
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