A New Method for Isolating and Purifying Natural Drug Taxol

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A New Method for Isolating and Purifying Natural Drug Taxol

XIAO Jian; HAN Jinyu; MA Peisheng

College of Chemical Engineering, Tianjin University, Tianjin 300072, China

Received:1900-01-01 Revised:1900-01-01 Online:2002-12-28 Published:2002-12-28
Contact: XIAO Jian

一种分离纯化天然药物紫杉醇的新方法

肖剑; 韩金玉; 马沛生

College of Chemical Engineering, Tianjin University, Tianjin 300072, China

通讯作者: 肖剑

Abstract

Abstract: A pharmacological interaction target (PIT) method for solving the difficult problem in the
separation of taxol from cephalonmanine was proposed. A two-phase extraction technique was
used to carry out the PIT separation process. The effects of buffer, temperature and
protein on the separation were investigated. Feasible disassembly conditions were also
discussed. The final purity of taxol can reach 95% or higher.

Key words: taxol, purification, pharmacological interaction target method

摘要： A pharmacological interaction target (PIT) method for solving the difficult problem in the
separation of taxol from cephalonmanine was proposed. A two-phase extraction technique was
used to carry out the PIT separation process. The effects of buffer, temperature and
protein on the separation were investigated. Feasible disassembly conditions were also
discussed. The final purity of taxol can reach 95% or higher.

关键词: taxol;purification;pharmacological interaction target method

XIAO Jian, HAN Jinyu, MA Peisheng. A New Method for Isolating and Purifying Natural Drug Taxol[J]. .

肖剑, 韩金玉, 马沛生. 一种分离纯化天然药物紫杉醇的新方法[J]. CIESC Journal.

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