化工学报 ›› 2022, Vol. 73 ›› Issue (6): 2698-2707.doi: 10.11949/0438-1157.20220089
万景1(),张霖2,樊亚超2,刘勰民1,骆培成3,张锋1(
),张志炳1
Jing WAN1(),Lin ZHANG2,Yachao FAN2,Xiemin LIU1,Peicheng LUO3,Feng ZHANG1(
),Zhibing ZHANG1
摘要:
对于通气搅拌式工业生物反应器的放大设计而言,精确预测气泡尺寸和体积传质系数非常重要,因此需要建立合适的气泡聚并和破碎模型,以保证反应器的高效操作。以5 L通气搅拌式生物反应器为对象,以气泡尺寸和体积传质系数的实验数据为基准,模拟并考察了两种聚并模型和四种破碎模型对生物反应器内流体流动行为以及传质能力的影响。结果表明,基于介尺度理论的修正聚并模型与考虑黏流剪切的破碎模型组合,所得模拟结果与实验数据吻合最好,这为大型生物反应器的桨型优化提供了模型基础。因为工业化生物发酵通常是在大型生物反应器中进行,搅拌桨型对生物反应器效能至关重要,故本研究在选定最优气泡聚并破碎模型的基础上,通过叶轮末端剪切力相等的放大原则将5 L通气搅拌式工业生物反应器放大到400 m3,同时考察了六斜叶圆盘搅拌桨、非对称式抛物线搅拌桨、布鲁马金式搅拌桨以及六直叶圆盘搅拌桨等桨型组合对气泡破碎能力和气体分散效果的影响,并通过综合对比气含率、体积传质系数等参数,得到400 m3通气搅拌式生物反应器的最优桨型组合。
中图分类号:
8 | Yang N, Xiao Q. A mesoscale approach for population balance modeling of bubble size distribution in bubble column reactors[J]. Chemical Engineering Science, 2017, 170: 241-250. |
9 | 肖颀, 杨宁. 基于EMMS模型的搅拌釜内气液两相流数值模拟[J]. 化工学报, 2016, 67(7): 2732-2739. |
Xiao Q, Yang N. Numerical simulation of gas-liquid flow in stirred tanks based on EMMS model[J]. CIESC Journal, 2016, 67(7): 2732-2739. | |
10 | Luo H A, Svendsen H F. Theoretical model for drop and bubble breakup in turbulent dispersions[J]. AIChE Journal, 1996, 42(5): 1225-1233. |
11 | Han L C, Luo H A, Liu Y J. A theoretical model for droplet breakup in turbulent dispersions[J]. Chemical Engineering Science, 2011, 66(4): 766-776. |
12 | Han L C, Gong S G, Li Y Q, et al. Influence of energy spectrum distribution on drop breakage in turbulent flows[J]. Chemical Engineering Science, 2014, 117: 55-70. |
13 | Han L C, Gong S G, Ding Y W, et al. Consideration of low viscous droplet breakage in the framework of the wide energy spectrum and the multiple fragments[J]. AIChE Journal, 2015, 61(7): 2147-2168. |
14 | Solsvik J, Tangen S, Jakobsen H A. On the constitutive equations for fluid particle breakage[J]. Reviews in Chemical Engineering, 2013, 29(5): 241-356. |
15 | Shi W B, Yang X G, Sommerfeld M, et al. Modelling of mass transfer for gas-liquid two-phase flow in bubble column reactor with a bubble breakage model considering bubble-induced turbulence[J]. Chemical Engineering Journal, 2019, 371: 470-485. |
16 | Luo P, Wu J, Pan X, et al. Gas-liquid mass transfer behavior in a surface-aerated vessel stirred by a novel long-short blades agitator[J]. AIChE Journal, 2016, 62(4): 1322-1330. |
17 | Martínez-Delgadillo S A, Alonzo-Garcia A, Mendoza-Escamilla V X, et al. Analysis of the turbulent flow and trailing vortices induced by new design grooved blade impellers in a baffled tank[J]. Chemical Engineering Journal, 2019, 358: 225-235. |
18 | Mule G M, Kulkarni A A. Mixing of medium viscosity liquids in a stirred tank with fractal impeller[J]. Theoretical Foundations of Chemical Engineering, 2016, 50(6): 914-921. |
1 | Straathof A J J, Wahl S A, Benjamin K R, et al. Grand research challenges for sustainable industrial biotechnology[J]. Trends in Biotechnology, 2019, 37(10): 1042-1050. |
2 | Amer B, Baidoo E E K. Omics-driven biotechnology for industrial applications[J]. Frontiers in Bioengineering and Biotechnology, 2021, 9: 613307. |
19 | Gaddis E S. Mass transfer in gas-liquid contactors[J]. Chemical Engineering and Processing: Process Intensification, 1999, 38(4/5/6): 503-510. |
20 | Montante G, Horn D, Paglianti A. Gas-liquid flow and bubble size distribution in stirred tanks[J]. Chemical Engineering Science, 2008, 63(8): 2107-2118. |
21 | Khopkar A R, Rammohan A R, Ranade V V, et al. Gas-liquid flow generated by a Rushton turbine in stirred vessel: CARPT/CT measurements and CFD simulations[J]. Chemical Engineering Science, 2005, 60(8/9): 2215-2229. |
22 | Sanyal J, Vásquez S, Roy S, et al. Numerical simulation of gas-liquid dynamics in cylindrical bubble column reactors[J]. Chemical Engineering Science, 1999, 54(21): 5071-5083. |
23 | van Baten J M, Krishna R. CFD simulations of a bubble column operating in the homogeneous and heterogeneous flow regimes[J]. Chemical Engineering & Technology, 2002, 25(11): 1081-1086. |
24 | Schiller L, Naumann A. A drag coefficient correlation[J]. Zeitschrift des Vereins Deutscher Ingenieure, 1935, 77: 318-320. |
25 | Orszag S A, Yakhot V, Flannery W S, et al. Renormalization group modeling and turbulence simulations[C]// Proceedings of International Conference on Near-Wall Turbulent Flows. 1993. |
26 | Prince M J, Blanch H W. Bubble coalescence and break-up in air-sparged bubble columns[J]. AIChE Journal, 1990, 36(10): 1485-1499. |
27 | Wang T F, Wang J F, Jin Y. A novel theoretical breakup kernel function for bubbles/droplets in a turbulent flow[J]. Chemical Engineering Science, 2003, 58(20): 4629-4637. |
28 | Garcia-Ochoa F, Gomez E. Bioreactor scale-up and oxygen transfer rate in microbial processes: an overview[J]. Biotechnology Advances, 2009, 27(2): 153-176. |
29 | Danckwerts P V. Significance of liquid-film coefficients in gas absorption[M]//Insights Into Chemical Engineering. Amsterdam: Elsevier, 1981: 51-75. |
30 | Kerdouss F, Bannari A, Proulx P, et al. Two-phase mass transfer coefficient prediction in stirred vessel with a CFD model[J]. Computers & Chemical Engineering, 2008, 32(8): 1943-1955. |
31 | Xiao H, Geng S J, Chen A Q, et al. Bubble formation in continuous liquid phase under industrial jetting conditions[J]. Chemical Engineering Science, 2019, 200: 214-224. |
3 | Maluta F, Paglianti A, Montante G. Modelling of biohydrogen production in stirred fermenters by computational fluid dynamics[J]. Process Safety and Environmental Protection, 2019, 125: 342-357. |
4 | Wang H N, Jia X Q, Wang X, et al. CFD modeling of hydrodynamic characteristics of a gas-liquid two-phase stirred tank[J]. Applied Mathematical Modelling, 2014, 38(1): 63-92. |
5 | Shen X Z, Hibiki T. Bubble coalescence and breakup model evaluation and development for two-phase bubbly flows[J]. International Journal of Multiphase Flow, 2018, 109: 131-149. |
6 | Zhang X B, Luo Z H. Effects of bubble coalescence and breakup models on the simulation of bubble columns[J]. Chemical Engineering Science, 2020, 226: 115850. |
7 | Luo H. Coalescence, breakup and liquid circulation in bubble column reactors[D]. Trondheim: Norwegian Institute of Technology, 1993. |
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