基于双部分丢弃的模拟移动床产率提高策略

doi:10.11949/0438-1157.20220108

化工学报 ›› 2022, Vol. 73 ›› Issue (7): 3099-3108.doi: 10.11949/0438-1157.20220108

基于双部分丢弃的模拟移动床产率提高策略

魏朋(),陈珺(),王志国,刘飞

江南大学轻工过程先进控制教育部重点实验室，江苏无锡 214122

收稿日期:2022-01-19 修回日期:2022-03-19 出版日期:2022-07-05 发布日期:2022-08-01
通讯作者: 陈珺 E-mail:6191913036@stu.jiangnan.edu.cn;chenjun1860@126.com
作者简介:魏朋(1995—)，男，硕士研究生，6191913036@stu.jiangnan.edu.cn
基金资助:
国家自然科学基金面上项目(61773183)

Improved productivity strategy of simulated moving bed based on binary-partial-discard

Peng WEI(),Jun CHEN(),Zhiguo WANG,Fei LIU

Key Laboratory of Advanced Control for Light Industry Process of the Ministry of Education, Jiangnan University, Wuxi 214122, Jiangsu, China

Received:2022-01-19 Revised:2022-03-19 Published:2022-07-05 Online:2022-08-01
Contact: Jun CHEN E-mail:6191913036@stu.jiangnan.edu.cn;chenjun1860@126.com

摘要/Abstract

摘要：

在保证产品纯度的情况下，提出一种带额外色谱柱的双部分丢弃策略以提高模拟移动床的产率。通过将工艺点选取在纯提取产品和非纯提余产品区域以增大进料流量，并将由此导致的含较多杂质的提余产品暂时丢弃。丢弃的提余产品作为循环进料通入到一个额外色谱柱中以进一步分离，部分不能达到指定纯度的额外产品被永久丢弃。在模拟移动床和额外色谱柱处分别收集到的产品组成总产品。分析了工艺点的选取、提余产品的积分纯度阈值和额外产品的积分纯度阈值对总产品性能参数的影响。研究结果表明，所提策略能够以较高的回收率利用原料，且能够显著提高分离过程的产率，其分离效果优于传统的模拟移动床工艺和部分丢弃策略。

关键词: 模拟移动床, 色谱, 产率, 平衡理论, 额外色谱柱, 部分丢弃, 优化设计

Abstract:

Under the condition of ensuring the purity of products, an extra-column and binary-partial-discard strategy is proposed to improve the productivity of the simulated moving bed. The process point is selected in the area of pure extract products and non-pure raffinate products to increase the feed flow, and the raffinate products with more impurities is temporarily discarded. The discarded raffinate products is fed as a recycling feed into an extra chromatographic column for further separation, some extra products that cannot reach the specified purity are permanently discarded. In this way, the total products consist of the products collected at the simulated moving bed and the extra chromatographic column respectively. This paper analyzes the effects of the selection of process point, the integral purity threshold of raffinate products and the integral purity threshold of extra products on the performance parameters of total products. The research results show that the proposed strategy can not only use raw materials with high recovery rate, but also can significantly improve the productivity of the simulated moving bed, and its separation effect is better than the conventional simulated moving bed process as well as than the partial-discard strategy.

Key words: simulated moving bed, chromatography, productivity, equilibrium theory, extra-column, partial-discard, optimal design

中图分类号:

TQ 028.8

魏朋, 陈珺, 王志国, 刘飞. 基于双部分丢弃的模拟移动床产率提高策略[J]. 化工学报, 2022, 73(7): 3099-3108.

WEI Peng, CHEN Jun, WANG Zhiguo, LIU Fei. Improved productivity strategy of simulated moving bed based on binary-partial-discard[J]. CIESC Journal, 2022, 73(7): 3099-3108.

图/表 14

图1

图2

图3

图4

图5

表1

图6

表2

模拟移动床运行在新工艺点时所获得的性能参数"

Run	$m Ⅱ$	$m Ⅲ$	Pu_A/%	Pu_B/%	Re_A/%	Re_B/%
1	0.2850	0.5489	97.61	95.10	90.57	96.50
2	0.2900	0.5539	98.21	94.07	89.42	97.44
3	0.2950	0.5589	98.68	92.93	88.17	98.26
4	0.3000	0.5639	99.07	91.77	86.74	98.89
5	0.3050	0.5689	99.35	90.56	85.22	99.40
6	0.3100	0.5739	99.56	89.16	83.72	99.90
$?$	$?$	$?$	$?$	$?$	$?$	$?$
24	0.4000	0.6639	99.90	67.17	51.04	99.90
25	0.4050	0.6689	99.90	66.37	49.17	99.91
26	0.4100	0.6739	99.91	65.62	47.31	99.93

表2

图7

图8

表3

提余产品在不同纯度阈值下进行部分丢弃后的性能参数"

Run	纯度阈值/%	纯度/%	回收率/%
1	98.00	98.02	69.91
2	98.10	98.11	69.21
3	98.20	98.23	68.26
4	98.30	98.31	67.56
5	98.40	98.42	66.61
6	98.50	98.51	65.91
7	98.60	98.61	64.96
$?$	$?$	$?$	$?$
15	99.40	99.41	53.92
16	99.50	99.50	51.34
17	99.60	99.60	47.37

表3

图9

图10

图11

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模型参数		初始工艺参数
柱分布结构	2-2-2-2	A的进料浓度	0.5 g/ml
组分数	2	B的进料浓度	0.5 g/ml
柱长	53.6 cm	进料液流量	0.0200 ml/s
柱直径	2.6 cm	洗脱液流量	0.0414 ml/s
空隙率	0.38	提取液流量	0.0348 ml/s
轴向扩散系数	0.0381 cm²/s	提余液流量	0.0266 ml/s
A的亨利系数	0.54	循环液流量	0.0981 ml/s
B的亨利系数	0.28	切换时间	1552 s

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基于双部分丢弃的模拟移动床产率提高策略

Improved productivity strategy of simulated moving bed based on binary-partial-discard

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